TY  -  JOUR
AU  -  A cura della Redazione
T1  -  L’uso cronico di oppioidi aumenta la sensibilità al dolore?
PY  -  2017
Y1  -  2017-04-01
DO  -  10.1702/2721.27756
JO  -  Assistenza Infermieristica e Ricerca
JA  -  Assist Inferm Ric
VL  -  36
IS  -  2
SP  -  101
EP  -  103
PB  -  Il Pensiero Scientifico Editore
SN  -  2038-1778
Y2  -  2026/04/22
UR  -  http://dx.doi.org/10.1702/2721.27756
N2  -  Summary. Do opioids make chronic users more sensitive to pain? At high doses opioids seem to amplify pain by changing signaling in the central nervous system, making the body more sensitive to pain. This phenomenon is already known but difficult to diagnose, thus its prevalence is unknown. It is assumed that it could play a role in the epidemics of opioids abuse. The mechanisms of opioids induced hyperalgesia and the most recent research to describe and revers it are described.
ER  -